Edaravone dexborneol ameliorates cognitive impairment by regulating the NF-κB pathway through AHR and promoting microglial polarization towards the M2 phenotype in mice with bilateral carotid artery stenosis (BCAS)
Lei Li, Guojun He, Mingyu Shi, Juehua Zhu, Yongqing Cheng, Yang Chen, Jin Chen, Qun Xue
Topics & Concepts
Morris water navigation taskProinflammatory cytokineMicrogliaNeuroinflammationNF-κBMedicinePharmacologyCognitive declineDownregulation and upregulationIκBαCancer researchChemistryEndocrinologyInflammationInternal medicineDementiaHippocampusBiochemistryGeneDiseaseNeuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and TreatmentsBarrier Structure and Function Studies