Just Add Water: Modulating the Structure-Derived Acidity of Catalytic Hexameric Resorcinarene Capsules
David A. Poole, Simon Mathew, Joost N. H. Reek
Abstract
enhances the catalytic rate of a model Diels-Alder cyclization by 10-fold, demonstrating the cofactor-derived control of a supramolecular catalytic process that emulates natural enzymatic systems.
Topics & Concepts
ResorcinareneChemistrySupramolecular chemistryCatalysisMoleculeHydrogen bondCalixareneStereochemistryNuclear magnetic resonance spectroscopyCombinatorial chemistryCrystallographyOrganic chemistrySupramolecular Chemistry and ComplexesCrystallography and molecular interactionsMass Spectrometry Techniques and Applications