Disulfidptosis in cancer: from redox stress to therapeutic strategy
Xinpei Deng, Chengyi Zhang, Jindong Xie, Binbin Tang, Xingliang Tan, Yutian Zou
Topics & Concepts
CrosstalkEndoplasmic reticulumRegulatorChemistryCancer therapyCell biologyCellProgrammed cell deathRedoxTranslation (biology)Tumor microenvironmentOxidative stressGlutathioneCancer researchCell growthTumor cellsCancer cellCellular stress responseUnfolded protein responseCell survivalCancer treatmentTumor progressionApoptosisIntracellularBioinformaticsCancerFight-or-flight responseBiochemistryMetabolic regulationPosttranslational modificationReactive oxygen speciesSignal transductionEndoplasmic Reticulum Stress and DiseaseRedox biology and oxidative stressSulfur Compounds in Biology