MAP2K1 Mutations in Advanced Colorectal Cancer Predict Poor Response to Anti-EGFR Therapy and to Vertical Targeting of MAPK Pathway
Jeremy Chuang, Chongkai Wang, Yuming Guo, Valerie Valenzuela, Jun Wu, Marwan Fakih
Topics & Concepts
MedicineColorectal cancerMAPK/ERK pathwayOncologyCancer researchInternal medicineCancerSignal transductionGeneticsBiologyMelanoma and MAPK PathwaysColorectal Cancer Treatments and StudiesLung Cancer Treatments and Mutations