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MAP2K1 Mutations in Advanced Colorectal Cancer Predict Poor Response to Anti-EGFR Therapy and to Vertical Targeting of MAPK Pathway

Jeremy Chuang, Chongkai Wang, Yuming Guo, Valerie Valenzuela, Jun Wu, Marwan Fakih

2020Clinical Colorectal Cancer31 citationsDOIOpen Access PDF

Topics & Concepts

MedicineColorectal cancerMAPK/ERK pathwayOncologyCancer researchInternal medicineCancerSignal transductionGeneticsBiologyMelanoma and MAPK PathwaysColorectal Cancer Treatments and StudiesLung Cancer Treatments and Mutations