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The central role of DNA damage in the ageing process

Björn Schumacher, Joris Pothof, Jan Vijg, Jan H.J. Hoeijmakers

2021Nature920 citationsDOIOpen Access PDF

Topics & Concepts

AgeingProteostasisBiologyPhenotypeDNA damageMechanism (biology)EpigenomicsComputational biologyNeuroscienceGeneticsDNA methylationDNAGeneGene expressionEpistemologyPhilosophyDNA Repair MechanismsTelomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
The central role of DNA damage in the ageing process | Litcius