Design, synthesis, and biological evaluation of phenyl thiazole-based AR-V7 degraders
Archana Bhumireddy, N.V.M. Rao Bandaru, B. Raghurami Reddy, Suraj T. Gore, Subhendu Mukherjee, Wesley Roy Balasubramanian, Vipin Kumar, Krishna Satya A, Kondapalli Venkata Gowri Chandra Sekhar, Kavitha Nellore, Chandrasekhar Abbineni, Susanta Samajdar
Topics & Concepts
ChemistrySmall moleculeComputational biologyDNAspliceCombinatorial chemistryCancer researchGeneBiochemistryBiologyComputational Drug Discovery MethodsProtein Degradation and InhibitorsPARP inhibition in cancer therapy