Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens
Atray Dixit, Oren Parnas, Biyu Li, Jenny Chen, Charles P. Fulco, Livnat Jerby‐Arnon, Nemanja D. Marjanovic, Danielle Dionne, Tyler Burks, Raktima Raychowdhury, Britt Adamson, Thomas M. Norman, Eric S. Lander, Jonathan S. Weissman, Nir Friedman, Aviv Regev
Topics & Concepts
BiologyComputational biologyRNA-SeqProfiling (computer programming)Gene expression profilingRNAGeneticsGeneGene expressionTranscriptomeComputer scienceOperating systemSingle-cell and spatial transcriptomicsCRISPR and Genetic EngineeringCell Image Analysis Techniques