In situ albumin-binding and esterase-specifically cleaved BRD4-degrading PROTAC for targeted cancer therapy
Hanhee Cho, Seong Ik Jeon, Man Kyu Shim, Cheol‐Hee Ahn, Kwangmeyung Kim
Topics & Concepts
Cancer therapyMaterials scienceIn situAlbuminEsteraseCancerCancer researchMedicineBiochemistryEnzymeChemistryInternal medicineOrganic chemistryProtein Degradation and InhibitorsMultiple Myeloma Research and TreatmentsUbiquitin and proteasome pathways