Genome mining reveals a new cyclopentane-forming sesterterpene synthase with unprecedented stereo-control
Yuben Qiao, Qiaoxin Xu, Zijian Huang, Xia Chen, Xiaomeng Ren, Wenling Yuan, Zhenhua Guan, Pengkun Li, Fengli Li, Chaomei Xiong, Hucheng Zhu, Chunmei Chen, Lianghu Gu, Yuan Zhou, Changxing Qi, Zhengxi Hu, Junjun Liu, Ying Ye, Yonghui Zhang
Abstract
Fungal bifunctional terpene synthase PstA catalyzes the formation of 5/15 cis -fused ring system.
Topics & Concepts
CyclopentaneChemistryATP synthaseComputational biologyBiochemistryStereochemistryEnzymeBiologyPlant biochemistry and biosynthesisMicrobial Natural Products and BiosynthesisPhotosynthetic Processes and Mechanisms