Synthesis and insight into the structure–activity relationships of 2-phenylbenzimidazoles as prospective anticancer agents
Thi‐Kim‐Chi Huynh, Thi‐Hong‐An Nguyen, Thi‐Cam‐Thu Nguyen, Thi‐Kim‐Dung Hoang
Abstract
against the MDA-MB-231 cell line. The results demonstrated that introducing a new substituent to compounds 37-55 could improve their antiproliferative activities.
Topics & Concepts
ChemistryCombinatorial chemistryPharmacologyStereochemistryNanotechnologyMedicineMaterials scienceSynthesis and biological activitySynthesis and Characterization of Heterocyclic CompoundsSynthesis and Biological Evaluation