CD44-targeted vesicles encapsulating granzyme B as artificial killer cells for potent inhibition of human multiple myeloma in mice
Yinan Zhong, Fenghua Meng, Wen Zhang, Bin Li, Jan C. M. van Hest, Zhiyuan Zhong
Topics & Concepts
Bone marrowGranzyme BHoming (biology)Cancer researchChemistryCD44BortezomibMultiple myelomaImmunologyMedicineImmune systemT cellCellBiologyBiochemistryEcologyMultiple Myeloma Research and TreatmentsProtein Degradation and InhibitorsImmunotherapy and Immune Responses