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ALS‐linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain‐of‐function

Devesh C. Pant, Janani Parameswaran, Lu Rao, Isabel Loss, Ganesh Chilukuri, Rosanna Parlato, Liang Shi, Jonathan D. Glass, Gary J. Bassell, Philipp Koch, Rüstem Yilmaz, Jochen H. Weishaupt, Arne Gennerich, Jie Jiang

2022EMBO Reports70 citationsDOIOpen Access PDF

Topics & Concepts

Amyotrophic lateral sclerosisMutationMutantBiologyGeneticsDrosophila melanogasterMechanism (biology)Ectopic expressionCell biologyGeneDiseaseMedicinePathologyPhilosophyEpistemologyAmyotrophic Lateral Sclerosis ResearchMicrotubule and mitosis dynamicsNeurogenetic and Muscular Disorders Research
ALS‐linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain‐of‐function | Litcius