Litcius/Paper detail

Discovery of a potent and highly selective inhibitor of ataxia telangiectasia mutated and Rad3-Related (ATR) kinase: Structural activity relationship and antitumor activity both in vitro and in vivo

Huachao Bin, Pei Chen, Ming Wu, Falu Wang, Guifeng Lin, Shulei Pan, Jingming Liu, Bo Mu, Jinshan Nan, Qiao Huang, Linli Li, Shengyong Yang

2022European Journal of Medicinal Chemistry26 citationsDOIOpen Access PDF

Topics & Concepts

In vivoKinaseChemistryAtaxia-telangiectasiaIn vitroDNA damageBiochemistryCancer researchPharmacologyDNABiologyGeneticsDNA Repair MechanismsCancer therapeutics and mechanismsCancer-related Molecular Pathways