Focused ultrasound blood brain barrier opening mediated delivery of MRI-visible albumin nanoclusters to the rat brain for localized drug delivery with temporal control
Megan Rich, Jennifer Sherwood, Aundrea F. Bartley, Quentin A. Whitsitt, Magdelene Lee, William R. Willoughby, Lynn E. Dobrunz, Yuping Bao, Farah D. Lubin, Mark Bolding
Topics & Concepts
NanoclustersIn vivoDrug deliveryBlood–brain barrierMicrobubblesDrug delivery to the brainMedicineAlbuminDrugNeuroscienceUltrasoundBiomedical engineeringPathologyCentral nervous systemPharmacologyNanotechnologyMaterials scienceBiologyInternal medicineRadiologyBiotechnologyUltrasound and Hyperthermia ApplicationsPhotoacoustic and Ultrasonic ImagingHemoglobin structure and function