Novel approach for the detection of alkylated bases using the enzyme-modified comet assay
Damián Muruzabal, Julen Sanz-Serrano, Sylvie Sauvaigo, Kristine B. Gützkow, Adela López de Ceráin, Ariane Vettorazzi, Amaya Azqueta
Topics & Concepts
Comet assayChemistryDNA glycosylasePurine metabolismMolecular biologyBiochemistryHypoxanthineDNAPurineDNA damageEnzymeBiologyCarcinogens and Genotoxicity AssessmentAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid Chemistry