Hemophagocytic lymphohistiocytosis during pregnancy: a review of the literature in epidemiology, pathogenesis, diagnosis and treatment
Lidong Liu, Yutong Cui, Qiongjie Zhou, Huanqiang Zhao, Xiaotian Li
Abstract
Hemophagocytic lymphohistiocytosis during pregnancy is rare; it is often misdiagnosed, resulting in a high maternal and foetal mortality rate. Herein, based on limited case reports including antepartum and postpartum cases, we reviewed the current studies of pregnancy-related hemophagocytic lymphohistiocytosis, and compared the epidemiology, aetiology, diagnosis and treatment of pregnancy-related hemophagocytic lymphohistiocytosis with non-pregnancy, enriching the understanding of hemophagocytic lymphohistiocytosis and its treatment in obstetrics.
Topics & Concepts
Hemophagocytic lymphohistiocytosisPregnancyMedicineEtiologyEpidemiologyIntensive care medicinePediatricsObstetricsImmunologyDiseaseInternal medicineBiologyGeneticsAutoimmune and Inflammatory Disorders ResearchAdolescent and Pediatric HealthcareParvovirus B19 Infection Studies