Protein S-nitrosylation regulates proteostasis and viability of hematopoietic stem cell during regeneration
Weiwei Yi, Yuying Zhang, Bo Liu, Yuanyuan Zhou, Dandan Liao, Xinhua Qiao, Dan Gao, Ting Xie, Qin Yao, Yao Zhang, Yugang Qiu, Gang Huang, Zhiyang Chen, Chang Chen, Zhenyu Ju
Abstract
HSCs. These findings establish a link between S-nitrosylation and protein aggregation in HSC in the context of blood regeneration.
Topics & Concepts
S-NitrosylationCell biologyProteostasisHaematopoiesisStem cellRegeneration (biology)Hematopoietic stem cellBiologyChemistryNitrosylationContext (archaeology)Nitric oxideBiochemistryEnzymeCysteineEndocrinologyPaleontologyHemoglobin structure and functionErythrocyte Function and PathophysiologyCancer, Hypoxia, and Metabolism