Investigation of cardiolipin oxidation products as a new endpoint for oxidative stress in C. elegans by means of online two-dimensional liquid chromatography and high-resolution mass spectrometry
Patrick O. Helmer, Merle M. Nicolai, Vera Schwantes, Julia Bornhorst, Heiko Hayen
Topics & Concepts
Oxidative stressCardiolipinChemistryNeurodegenerationOxidative phosphorylationCaenorhabditis elegansLipidomeReactive oxygen speciesMitochondrionProteomicsLiquid chromatography–mass spectrometryBiochemistryPhospholipidLipidomicsMass spectrometryChromatographyMembraneDiseasePathologyGeneMedicineGenetics, Aging, and Longevity in Model OrganismsMitochondrial Function and PathologyMetabolomics and Mass Spectrometry Studies