Design, synthesis, crystal structure, photophysical behavior and aggregation-induced emission of a novel pyrene scaffold multifunctional Schiff base ligand: inhibition of digestive enzymes and docking studies
Naba Kr Mandal, Priyanka Arya, Neera Raghav, Shubhamoy Chowdhury, Jnan Prakash Naskar
Abstract
A novel pyrene-imidazole based Schiff base condensate, 2-(2-(pyren-1-ylmethylene)hydrazineyl)-4,5-dihydro 1 H -imidazole hydrobromide monohydrate (PI), has been synthesized.
Topics & Concepts
ChemistrySchiff baseImidazolePyreneHydrobromideDocking (animal)Aggregation-induced emissionScaffoldEnzymeStereochemistryLigand (biochemistry)Combinatorial chemistryOrganic chemistryBiochemistryFluorescenceReceptorNursingMedicineQuantum mechanicsBiomedical engineeringPhysicsLuminescence and Fluorescent MaterialsMolecular Sensors and Ion DetectionNanoplatforms for cancer theranostics