Furan-2-carboxamide derivative, a novel microtubule stabilizing agent induces mitotic arrest and potentiates apoptosis in cancer cells
Bettaswamigowda Shwetha, M. Srinivasa Sudhanva, Gullahalli S. Jagadeesha, N. R. Thimmegowda, Vivek K. Hamse, B. Sridhar, Kuntebommanahalli N. Thimmaiah, C. S. Ananda Kumar, Shobith Rangappa, Kanchugarakoppal S. Rangappa
Topics & Concepts
ChemistryTubulinMicrotubule polymerizationCancer cellCell biologyCell cycle checkpointCell cycleMitosisHeLaMicrotubuleAnnexinApoptosisCancer researchCellCancerBiochemistryBiologyGeneticsMicrotubule and mitosis dynamics14-3-3 protein interactionsUbiquitin and proteasome pathways