Trivalent cation-induced phase separation in proteins: ion specific contribution in hydration also counts
Ria Saha, Rajib Kumar Mitra
Abstract
)) measurements in the THz frequency domain we estimate the various stretching/vibrational modes of water and we found that ions, forming LLPS, produce definite perturbation in the overall hydration, the extent of which is ion specific, invoking the definite role of hydrophilic (electrostatic) hydration of ions in the observed LLPS process.
Topics & Concepts
ChemistryIonGlobular proteinPhase (matter)Chemical physicsMetal ions in aqueous solutionMetalAnalytical Chemistry (journal)CrystallographyChromatographyOrganic chemistrySpectroscopy and Quantum Chemical StudiesProtein Structure and DynamicsMass Spectrometry Techniques and Applications