Design and synthesis of isoniazid-based pyrazolines as potential inhibitors of Mycobacterium tuberculosis with promising radical scavenging action: In-vitro and in-silico evaluations
Jyoti Rasgania, Renu Gavadia, Mandira Varma‐Basil, Varsha Chauhan, Sanjay Kumar, Satbir Mor, Devender Singh, Komal Jakhar
Topics & Concepts
ChemistryIn silicoAntimycobacterialSubstituentPyrazolineIsoniazidMycobacterium tuberculosisDocking (animal)Combinatorial chemistryStereochemistryINHAIn vitroTuberculosisBiochemistryOrganic chemistryPathologyMedicineNursingGeneSynthesis and biological activityMulticomponent Synthesis of HeterocyclesSynthesis and Biological Evaluation