Pterostilbene attenuates RIPK3-dependent hepatocyte necroptosis in alcoholic liver disease via SIRT2-mediated NFATc4 deacetylation
Yunyun Shao, Xinqi Wang, Ying Zhou, Yiming Jiang, Ruoman Wu, Chunfeng Lu
Topics & Concepts
NecroptosisHepatocyteAlcoholic liver diseaseChemistryProinflammatory cytokineSteatosisOxidative stressCell biologyProgrammed cell deathCancer researchPterostilbenePharmacologyInflammationBiologyBiochemistryInternal medicineImmunologyMedicineEndocrinologyApoptosisIn vitroResveratrolCirrhosisAlcohol Consumption and Health EffectsHeme Oxygenase-1 and Carbon MonoxideLiver Disease Diagnosis and Treatment