Comparison and Contrast of Bone and Dentin in Genetic Disorder, Morphology and Regeneration: A Review
Jae Hyun Kim, Gayeong Lee, Woo Sung Chang, Si Hyoung Ki, Joo‐Cheol Park
Abstract
The bone and dentin have distinct healing processes. The healing process of bones is regenerative, as newly formed tissues are morphologically and functionally similar to the original bone structures. In contrast, the healing process of dentin is reparative due to its failure to replicate some of its key morphological features. In this review, we compare and contrast the healing processes of bone and dentin. We describe how distinct morphological and physiological structures of the 2 tissues translate into different signaling molecules, growth factors, and matrix protein secretion.
Topics & Concepts
DentinDentinogenesisRegeneration (biology)Bone healingDentistryCell biologyAnatomyMedicineBiologyOdontoblastBone and Dental Protein Studiesdental development and anomaliesEndodontics and Root Canal Treatments