Development of a two-photon fluorescent probe for imaging hydrogen sulfide (H<sub>2</sub>S) in living cells and zebrafish
Xu Chen, Yukun Zhang, Hui Sun, Jindong Ai, Mingguang Ren
Abstract
The probe T-HS was developed as a fluorescent H 2 S probe using 1,8-naphthylamine as fluorescent platform and azide group as the reaction site, which can be effectively used for fluorescence imaging of endogenous and exogenous H 2 S in zebrafish and cells.
Topics & Concepts
FluorescenceZebrafishHydrogen sulfideChemistryTwo-photon excitation microscopyLive cell imagingEndogenyBiophysicsPhotochemistryBiochemistryCellBiologyOpticsPhysicsSulfurOrganic chemistryGeneSulfur Compounds in BiologyNeuroscience of respiration and sleepMolecular Sensors and Ion Detection