In vitro antimicrobial evaluation and in silico studies of coumarin derivatives tagged with pyrano-pyridine and pyrano-pyrimidine moieties as DNA gyrase inhibitors
Eman A. Fayed, Eman S. Nosseir, Ahmed Atef, Samar El‐Kalyoubi
Topics & Concepts
ChemistryCoumarinDNA gyraseBenzoyl chlorideTriethyl orthoformateAntimicrobialTopoisomerase IVMalononitrilePyrimidinePyridineCombinatorial chemistryOrganic chemistryStereochemistryEscherichia coliBiochemistryGeneCatalysisSynthesis and biological activitySynthesis and Biological EvaluationMulticomponent Synthesis of Heterocycles