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Design, synthesis and molecular docking of new pyrazole-thiazolidinones as potent anti-inflammatory and analgesic agents with TNF-α inhibitory activity

Somaia S. Abd El‐Karim, Hanaa S. Mohamed, Mohamed F. Abdelhameed, Abd El‐Galil E. Amr, Abdulrahman A. Almehizia, Eman S. Nossier

2021Bioorganic Chemistry96 citationsDOI

Topics & Concepts

ChemistryPyrazoleDiclofenacAnalgesicDocking (animal)CelecoxibIn vivoAnti-inflammatoryPharmacologyStereochemistryCombinatorial chemistryBiochemistryBiologyBiotechnologyMedicineNursingSynthesis and biological activityInflammatory mediators and NSAID effectsSynthesis of heterocyclic compounds
Design, synthesis and molecular docking of new pyrazole-thiazolidinones as potent anti-inflammatory and analgesic agents with TNF-α inhibitory activity | Litcius