Regeneration of pulpo-dentinal–like complex by a group of unique multipotent CD24a <sup>+</sup> stem cells
Hong Chen, Huancheng Fu, Xue shuang Wu, Yufeng Duan, Sicheng Zhang, Hong Hu, Yuansong Liao, Tao Wang, Ying Yang, Guoqing Chen, Zhonghan Li, Weidong Tian
Abstract
cells could be detected in primary dental papilla in mice and human, suggesting that MDPSCs resided in their native niches. Together, our study has identified a previously unidentified group of multipotent pulp regenerative stem cells with defined molecular markers for the potential treatment of pulpitis and pulp necrosis.
Topics & Concepts
Dental papillaDental pulp stem cellsPulp (tooth)Multipotent Stem CellStem cellOdontoblastRegeneration (biology)Cell biologyBiologyPulpitisDentinDentistryAnatomyMedicineProgenitor cellMesenchymal stem cell researchdental development and anomaliesBone and Dental Protein Studies