Fabrication and characterization of a pro-angiogenic hydrogel derived from the human placenta
Ningning Chao, Jiale Li, Wei Ding, Tingwu Qin, Yi Zhang, Huiqi Xie, Jingcong Luo
Abstract
analyses confirmed that the placenta hydrogel exerted better pro-angiogenic effects than a collagen type I hydrogel. Histological data also showed that the placenta hydrogels did not elicit a grave inflammatory response. In conclusion, the results suggest that placenta hydrogels may be deemed an attractive scaffold for regenerative medicine applications, especially in promoting vessel formation.
Topics & Concepts
Self-healing hydrogelsDecellularizationPlacentaExtracellular matrixChemistryAngiogenesisIn vivoBiomedical engineeringTissue engineeringCell biologyGlycosaminoglycanIn vitroRegenerative medicineBiophysicsBiochemistryBiologyCancer researchMedicineFetusCellPregnancyGeneticsOrganic chemistryBiotechnologyTissue Engineering and Regenerative MedicineElectrospun Nanofibers in Biomedical ApplicationsCongenital heart defects research