Increasing breast milk betaine modulates <i>Akkermansia</i> abundance in mammalian neonates and improves long-term metabolic health
Sílvia Ribó, David Sánchez‐Infantes, Laura Martinez-Guino, Izaskun García‐Mantrana, Marta Ramon‐Krauel, Mireia Tondo, Erland Arning, Miquel Nofrarías, Óscar Osorio-Conles, Antonio Fernández-Pérez, Pedro González‐Torres, Judith Cebrià, Aleix Gavaldà‐Navarro, Empar Chenoll, Elvira Isganaitis, Francesc Villarroya, Mario Vallejo, Joaquím Segalés, Josep C. Jiménez‐Chillarón, Teodoro Bottiglieri, Ellen W. Demerath, David A. Fields, María Carmen Collado, Carles Lerín
Abstract
to mouse pups during the lactation period partially replicated the effects of maternal breast milk betaine, including increased intestinal goblet cell number, lower adiposity, and improved glucose homeostasis during adulthood. These data demonstrate a link between breast milk betaine content and long-term metabolic health of offspring.