<i>Lactobacillus rhamnosus</i> Probio-M9 alleviates OVA-sensitized food allergy through modulating gut microbiota and its metabolism
Jialu Shi, Pengfei Dong, Cheng Liu, Yan Xu, Mingzhu Zheng, Lei Cheng, Jin Wang, Vijaya Raghavan
Abstract
in the feces after Probio-M9 intake. Simultaneously, Probio-M9 significantly increased the levels of SCFAs and promoted the phosphorylation of signal transducer and activator of transcription 3 (STAT3), thereby inducing the expression of the antimicrobial peptides (AMPs) Reg3b and Reg3g. Our findings suggest that the use of Probio-M9 can be a potent strategy in food allergy prevention.
Topics & Concepts
Lactobacillus rhamnosusImmune systemFood allergyLactobacillusMicrobiomeMicrobiologyProbioticGut floraAllergyGut microbiomeImmunologyBiologyBacteriaBioinformaticsGeneticsProbiotics and Fermented FoodsFood Allergy and Anaphylaxis ResearchGut microbiota and health