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The neuroprotective effects of phosphocreatine on Amyloid Beta 25–35-induced differentiated neuronal cell death through inhibition of AKT /GSK-3β /Tau/APP /CDK5 pathways in vivo and vitro

Jie Ai, Hongyan Wang, Peng Chu, Abdullah Shopit, Mengyue Niu, Nisar Ahmad, Tsehaye Tesfaldet, Fu Han Wang, Jia Ni Fang, Xiaodong Li, Shi Jie Tang, Qing Ju Han, Guozhu Han, Jinyong Peng, Zeyao Tang

2020Free Radical Biology and Medicine20 citationsDOI

Topics & Concepts

Protein kinase BApoptosisChemistryPhosphocreatineGSK-3Molecular biologyCell biologyGSK3BPI3K/AKT/mTOR pathwayBiologyPhosphorylationBiochemistryEndocrinologyEnergy metabolismAlzheimer's disease research and treatmentsMitochondrial Function and PathologyGenetics and Neurodevelopmental Disorders
The neuroprotective effects of phosphocreatine on Amyloid Beta 25–35-induced differentiated neuronal cell death through inhibition of AKT /GSK-3β /Tau/APP /CDK5 pathways in vivo and vitro | Litcius