Litcius/Paper detail

Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease

Jessica S. Sadick, Michael R. O’Dea, Philip Hasel, Taitea Dykstra, Arline Faustin, Shane A. Liddelow

2022Neuron404 citationsDOIOpen Access PDF

Topics & Concepts

BiologyTranscriptomeAstrocyteNeuroscienceApolipoprotein EAlzheimer's diseaseNeurogliaNeurodegenerationHuman brainMicrogliaDiseaseGene expressionGeneCentral nervous systemGeneticsPathologyImmunologyMedicineInflammationNeuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomicsMicroRNA in disease regulation