Litcius/Paper detail

Discovery of a potent Gilteritinib-based FLT3-PROTAC degrader for the treatment of Acute myeloid leukemia

Lei Ye, Zhenzhen Cui, Yu Sun, Haikun Zhou, Quanjin Rong, Dan Wang, Jiaming Jin, Qijian Zhang, Di Kang, Lihong Hu, Junwei Wang, Junwei Wang

2024Bioorganic Chemistry11 citationsDOI

Topics & Concepts

ChemistryMyeloid leukemiaCancer researchLeukemiaImmunologyMedicineProtein Degradation and InhibitorsMultiple Myeloma Research and TreatmentsUbiquitin and proteasome pathways