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Integrated single-cell transcriptome analysis of CD34 + enriched leukemic stem cells revealed intra- and inter-patient transcriptional heterogeneity in pediatric acute myeloid leukemia

Deepshi Thakral, Vivek Kumar Singh, Ritu Gupta, Nitu Jha, Aafreen Khan, Gurvinder Kaur, Sandeep Rai, Vijay Kumar, Manisha Supriya, Sameer Bakhshi, Rachna Seth

2022Annals of Hematology14 citationsDOI

Topics & Concepts

TranscriptomeDownregulation and upregulationBiologyStem cellMyeloid leukemiaCancer researchGeneCell cycleHaematopoiesisGene expressionMolecular biologyCell biologyGeneticsAcute Myeloid Leukemia ResearchCancer Genomics and DiagnosticsSingle-cell and spatial transcriptomics
Integrated single-cell transcriptome analysis of CD34 + enriched leukemic stem cells revealed intra- and inter-patient transcriptional heterogeneity in pediatric acute myeloid leukemia | Litcius