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Rosmarinic acid ameliorated cardiac dysfunction and mitochondrial injury in diabetic cardiomyopathy mice via activation of the SIRT1/PGC-1α pathway

Jiayu Diao, Hongmou Zhao, Penghua You, Hongjun You, Hao-Yu Wu, Xiling Shou, Gong Cheng

2021Biochemical and Biophysical Research Communications30 citationsDOI

Topics & Concepts

Diabetic cardiomyopathyMitochondrionCardiac function curveApoptosisOxidative stressInternal medicineAdenosine triphosphateEndocrinologyPolyol pathwayDownregulation and upregulationMedicineCardiomyopathyBiologyDiabetes mellitusChemistryPharmacologyBiochemistryHeart failureGeneAldose reductaseSirtuins and Resveratrol in MedicineAdipose Tissue and MetabolismAutophagy in Disease and Therapy
Rosmarinic acid ameliorated cardiac dysfunction and mitochondrial injury in diabetic cardiomyopathy mice via activation of the SIRT1/PGC-1α pathway | Litcius