Early diagnosis and treatment of osteoarthritis with a Au@PDA-WL NP nano-probe by photoacoustic imaging
Jingjing Shen, Wenwen Shi, Guan Liu, Wei Zhuang, Kang Wang, Yi Wang, Kangquan Shou, Weibing Wu, Xiaowen Liu, Quli Fan, Lei Zhang
Abstract
, and the enrichment of this nano-probe on cartilage tissue further resulted in the localized plasmon resonance coupling effect, inducing an enhancement in photothermal conversion capacity after the formation of aggregates. Besides, the catechol structure in the PDA shell could eliminate ROS to effectively delay the development of osteoarthrosis.
Topics & Concepts
Photoacoustic imaging in biomedicineNano-OsteoarthritisMaterials scienceBiomedical engineeringNanotechnologyMedicineOpticsComposite materialPathologyPhysicsAlternative medicineOsteoarthritis Treatment and MechanismsPhotoacoustic and Ultrasonic ImagingNanoplatforms for cancer theranostics