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The role of vaccines in the COVID-19 pandemic: what have we learned?

Florian Krammer

2023Seminars in Immunopathology62 citationsDOIOpen Access PDF

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged late in 2019 and caused the coronavirus disease 2019 (COVID-19) pandemic that has so far claimed approximately 20 million lives. Vaccines were developed quickly, became available in the end of 2020, and had a tremendous impact on protection from SARS-CoV-2 mortality but with emerging variants the impact on morbidity was diminished. Here I review what we learned from COVID-19 from a vaccinologist's perspective.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)Pandemic2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyCoronavirus InfectionsBetacoronavirusMedicinePneumoniaOutbreakInfectious disease (medical specialty)DiseaseInternal medicinePathologySARS-CoV-2 and COVID-19 ResearchVaccine Coverage and HesitancyCOVID-19 Clinical Research Studies