Synergetic osteogenesis of extracellular vesicles and loading RGD colonized on 3D-printed titanium implants
Shiqing Ma, Xuewen Li, Han Hu, Xinying Ma, Zhezhe Zhao, Shu Deng, Jie Wang, Leyu Zhang, Chenxuan Wu, Zihao Liu, Yonglan Wang
Abstract
In this study, EVs are anchored on titanium successfully in a method supported by a fusion peptide in order to promote the osteogenic. This method is more convenient and effective than typical modifying techniques.
Topics & Concepts
OsseointegrationTitaniumMesenchymal stem cellVesicleChemistryBiomedical engineeringMineralization (soil science)In vivoExtracellular matrixExtracellular vesiclesCell biologyExtracellular vesicleImplantNanotechnologyBiophysicsMaterials scienceBiochemistryMicrovesiclesBiologySurgeryMembraneMedicineNitrogenBiotechnologyGeneOrganic chemistrymicroRNAExtracellular vesicles in diseaseMicroRNA in disease regulationRNA Interference and Gene Delivery