Use of an optimised enzyme/prodrug combination for Clostridia directed enzyme prodrug therapy induces a significant growth delay in necrotic tumours

Alexandra M. Mowday, Ludwig J. Dubois, Aleksandra M. Kubiak, Jasmine V.E. Chan-Hyams, Christopher P. Guise, Amir Ashoorzadeh, Philippe Lambin, David F. Ackerley, Jeff B. Smaill, Nigel P. Minton, Jan Theys, Adam V. Patterson