De Novo Somatic Mosaicism of CYBB Caused by Intronic LINE-1 Element Insertion Resulting in Chronic Granulomatous Disease
Lang Yu, Wenhui Li, Ge Lv, Gan Sun, Lu Yang, Junjie Chen, Lina Zhou, Yuan Ding, Zhiyong Zhang, Xuemei Tang, Yunfei An, Xiaodong Zhao
Topics & Concepts
Chronic granulomatous diseaseBiologyPrimary immunodeficiencyGeneticsInsertionMutationGeneImmune systemNeutrophil, Myeloperoxidase and Oxidative MechanismsStudies on Chitinases and Chitosanasesvaccines and immunoinformatics approaches