Litcius/Paper detail

Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol

Egor A. Syroegin, Laurin Flemmich, Dorota Klepacki, Nora Vázquez‐Laslop, Ronald Micura, Yury S. Polikanov

2022Nature Structural & Molecular Biology88 citationsDOIOpen Access PDF

Topics & Concepts

Peptidyl transferaseRibosomeTranslation (biology)A-siteContext (archaeology)ChemistryRibosomal RNABiologyComputational biologyBiochemistryBinding siteRNAMessenger RNAGenePaleontologyBiochemical and Molecular ResearchRNA and protein synthesis mechanismsPeptidase Inhibition and Analysis