Litcius/Paper detail

Pyranoquinolone derivatives: A potent multi‐targeted pharmacological scaffold

Jasreen Uppal, Prince Ahad Mir, Apporva Chawla, Nishant Kumar, Gurinder Kaur, Preet Mohinder Singh Bedi, Divya Dhawal Bhandari

2022Journal of Heterocyclic Chemistry20 citationsDOI

Abstract

Abstract The search for new heterocyclic compounds with potential bioactivities continues despite the fact that extensive work has already been done on pyranoquinolones. Researchers throughout the world have used the pyranoquinolone nucleus extensively to generate a wide variety of bioactive heterocycles that target a wide spectrum of biological targets. An in‐depth investigation into possible pyranoquinolone derivatives and their pharmacological importance is the focus of this overview of synthetic techniques. Researchers and medicinal chemists can benefit from this review by developing new pyranoquinolone nucleus leads that are very effective and have fewer adverse effects than existing ones.

Topics & Concepts

ChemistryBroad spectrumScaffoldBiochemical engineeringNanotechnologyCombinatorial chemistryComputational biologyComputer scienceDatabaseBiologyMaterials scienceEngineeringSynthesis and Biological EvaluationPhenothiazines and Benzothiazines Synthesis and ActivitiesCancer therapeutics and mechanisms