Litcius/Paper detail

Myogenic Differentiation of Stem Cells for Skeletal Muscle Regeneration

Dengjie Yu, Zijun Cai, Daishi Li, Yi Zhang, Miao He, Yuntao Yang, Di Liu, Wenqing Xie, Yusheng Li, Wenfeng Xiao

2021Stem Cells International74 citationsDOIOpen Access PDF

Abstract

Stem cells have become a hot research topic in the field of regenerative medicine due to their self-renewal and differentiation capabilities. Skeletal muscle tissue is one of the most important tissues in the human body, and it is difficult to recover when severely damaged. However, conventional treatment methods can cause great pain to patients. Stem cell-based tissue engineering can repair skeletal muscle to the greatest extent with little damage. Therefore, the application of stem cells to skeletal muscle regeneration is very promising. In this review, we discuss scaffolds and stem cells for skeletal muscle regeneration and put forward our ideas for future development.

Topics & Concepts

Skeletal muscleRegeneration (biology)Stem cellRegenerative medicineMyocyteCell biologyTissue engineeringBiologyMedicineAnatomyBioinformaticsPathologyBiomedical engineeringTissue Engineering and Regenerative MedicineMuscle Physiology and DisordersPluripotent Stem Cells Research