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Genomic Analyses Identify Manganese Homeostasis as a Driver of Group B Streptococcal Vaginal Colonization

Lindsey R. Burcham, Madeline S. Akbari, Norhan Alhajjar, Rebecca A. Keogh, Jana N. Radin, Thomas E. Kehl‐Fie, Ashton T. Belew, Najib M. El-Sayed, Kevin S. McIver, Kelly S. Doran

2022mBio22 citationsDOIOpen Access PDF

Abstract

Morbidity and mortality associated with GBS begin with colonization of the female reproductive tract (FRT). To date, our understanding of the factors required for GBS persistence in this environment remain limited.

Topics & Concepts

BiologyMutantColonizationMicrobiologyStreptococcusGeneGeneticsBacteriaNeonatal and Maternal InfectionsPneumonia and Respiratory InfectionsStreptococcal Infections and Treatments
Genomic Analyses Identify Manganese Homeostasis as a Driver of Group B Streptococcal Vaginal Colonization | Litcius