Temporospatial regulation of intraflagellar transport is required for the endochondral ossification in mice
Hiroyuki Yamaguchi, Megumi Kitami, Karin Harumi Uchima Koecklin, He Li, Jianbo Wang, William R. Lagor, Daniel S. Perrien, Yoshihiro Komatsu
Topics & Concepts
Intraflagellar transportEndochondral ossificationCiliumCell biologyChondrocyteBiologyIndian hedgehogFibroblast growth factorOssificationAnatomySignal transductionHedgehog signaling pathwayCartilageMutantGeneticsReceptorGeneGenetic and Kidney Cyst DiseasesEpigenetics and DNA MethylationUrological Disorders and Treatments