Existing and Potential Applications of Elastography for Measuring the Viscoelasticity of Biological Tissues In Vivo
Kaiwen Zhang, Min Zhu, Evan Thomas, Sevan Hopyan, Yu Sun
Abstract
Mechanical tissue properties contribute to tissue shape change during development. Emerging evidence suggests that gradients of viscoelasticity correspond to cell movement and gene expression patterns. To accurately define mechanisms of morphogenesis, a combination of precise empirical measurements and theoretical approaches are required. Here, we review elastography as a method to characterize viscoelastic properties of tissue in vivo . We discuss its current clinical applications in mature tissues and its potential for characterizing embryonic tissues.
Topics & Concepts
ViscoelasticityElastographyMorphogenesisIn vivoBiological tissueBiologyUltrasound elastographyBiomedical engineeringCell biologyBiological systemMaterials scienceMedicineUltrasoundGeneRadiologyComposite materialBiochemistryBiotechnologyCellular Mechanics and InteractionsElasticity and Material ModelingUltrasound Imaging and Elastography