Two-component supramolecular hydrogel for controlled drug release
Anna K. Patterson, David K. Smith
Abstract
A hybrid gel has been developed by combining two supramolecular gelators. Each gelator endows the hybrid gel with its own characteristics. One gelator enables pH-mediated controlled release of the active pharmaceutical ingredient naproxen, while the other new gelator enhances mechanical stability. Self-assembly thus gives multi-functional gels with potential applications.
Topics & Concepts
Supramolecular chemistryComponent (thermodynamics)Self-healing hydrogelsDrug deliveryMaterials scienceNanotechnologyChemistryChemical engineeringPolymer chemistryCombinatorial chemistryOrganic chemistryMoleculeThermodynamicsEngineeringPhysicsSupramolecular Self-Assembly in MaterialsRNA Interference and Gene DeliverySupramolecular Chemistry and Complexes