Altered redox regulation and S-glutathionylation of BiP contribute to bortezomib resistance in multiple myeloma
Jie Zhang, Zhiwei Ye, Wei Chen, John Culpepper, Haiming Jiang, Lauren E. Ball, Shikhar Mehrotra, Anna Blumental‐Perry, Kenneth D. Tew, Danyelle M. Townsend
Topics & Concepts
BortezomibUnfolded protein responseChemistryProteasome inhibitorOxidative stressEndoplasmic reticulumGlutathioneCell biologyProteasomeMolecular biologyBiologyBiochemistryMultiple myelomaImmunologyEnzymeGlutathione Transferases and PolymorphismsEndoplasmic Reticulum Stress and DiseaseGenomics, phytochemicals, and oxidative stress