Bioprinting-based automated deposition of single cancer cell spheroids into oxygen sensor microelectrode wells
Johannes Dornhof, Viktoria Zieger, Jochen Kieninger, Daniel Frejek, Roland Zengerle, G. Urban, Sabrina Kartmann, Andreas Weltin
Abstract
With an advanced bioprinter, we print cancer cell spheroids directly into chip-based oxygen microsensors to determine single spheroid metabolism and drug responses.
Topics & Concepts
SpheroidMicroelectrode3D cell cultureBiomedical engineeringChemistryCellular pathologyMultielectrode arrayNanotechnologyMaterials scienceCellElectrodeIn vitroPathologyPhysical chemistryBiochemistryMedicine3D Printing in Biomedical ResearchMicrofluidic and Bio-sensing TechnologiesNeuroscience and Neural Engineering